Cabgolin (Dostinex)0.50 mg – 8 tablet

Cabergoline Information

What is this drug used for?

• It is used to treat health problems where there are high prolactin levels.
• It may be given to you for other reasons. Talk with the doctor.

Possible side effects

Cabergoline may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

• Constipation.
• Feeling dizzy, tired, or weak.
• Headache.
• Upset stomach.

Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment:

• Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
• Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain.
• Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight.
• Chest pain.
• Cough that does not go away.
• Very bad dizziness or passing out.
• Change in the way you act.
• Strong urges that are hard to control (such as eating, gambling, sex, or spending money).
• Back pain.
• Stomach pain.
• Seizures.
• Rarely, heart valve problems have happened with this drug. Call your doctor right away if you have a fast or abnormal heartbeat, shortness of breath, swelling in the arms or legs, or a big weight gain.

Storage and Stability

Store at 20°C to 25°C (68°F to 77°F). Dispense in original container.

Adverse Reactions

>10%:

Gastrointestinal: Nausea (27% to 29%)

Nervous system: Headache (26%), dizziness (15% to 17%)

1% to 10%:

Cardiovascular: Orthostatic hypotension (4%), peripheral edema (1%), hypotension (≤1%), palpitations (≤1%), syncope (≤1%)

Dermatologic: Acne vulgaris (≤1%), pruritus (≤1%)

Endocrine & metabolic: Hot flash (3%), dependent edema (1%)

Gastrointestinal: Constipation (7% to 10%), abdominal pain (5%), dyspepsia (2% to 5%), vomiting (2% to 4%), diarrhea (≤2%), flatulence (≤2%), xerostomia (≤2%), toothache (1%), anorexia (≤1%)

Genitourinary: Mastalgia (1% to 2%), dysmenorrhea (≤1%)

Nervous system: Fatigue (5% to 7%), vertigo (1% to 4%), depression (3%), pain (2%), drowsiness (≤2%), nervousness (≤2%), paresthesia (≤2%), lack of concentration (1%), anxiety (≤1%), insomnia (≤1%), malaise (≤1%)

Neuromuscular & skeletal: Asthenia (6%), arthralgia (1%)

Ophthalmic: Periorbital edema (1%), visual disturbance (≤1%)

Respiratory: Rhinitis (1%), throat irritation (1%), flu-like symptoms (≤1%)

<1%, postmarketing, and/or case reports: Aggressive behavior, alopecia, epistaxis, facial edema, heart valve disease, impulse control disorder, increased libido (including hypersexuality), pathological gambling, pericardial effusion, pleural effusion, psychosis, pulmonary fibrosis, retroperitoneal fibrosis, weight gain, weight loss