COBIX (Celebrex)200 mg – 100 tablet

Celecoxib Information

Pronunciation

(se le KOKS ib)

What is this drug used for?

• It is used to ease pain and swelling.

• It is used to treat arthritis.

• It is used to ease painful period (menstrual) cycles.

• It is used to treat ankylosing spondylitis.

• It may be given to you for other reasons. Talk with the doctor.

Frequently reported side effects of this drug

• Abdominal pain

• Heartburn

• Nausea

• Vomiting

• Constipation

• Diarrhea

• Passing gas

• Common cold symptoms

• Sore throat

• Stuffy nose

Medication Safety Issues
Sound-alike/look-alike issues:

CeleBREX may be confused with CeleXA, Cerebyx, Cervarix, Clarinex

Storage and Stability

Store at 20°C to 25°C (68°F to 77°F); excursions permitted to 15°C to 30°C (59°F to 86°F).

Adverse Reactions

Cardiovascular: Peripheral edema

Dermatologic: Acute generalized exanthematous pustulosis, exfoliative dermatitis

Gastrointestinal: Abdominal pain, diarrhea, dyspepsia, flatulence, gastroesophageal reflux disease, gastrointestinal perforation, gastrointestinaI ulcer, GI inflammation, intestinal perforation, vomiting

Hepatic: Increased liver enzymes (<3x ULN)

Hypersensitivity: Anaphylaxis

Immunologic: DRESS syndrome

Renal: Nephrolithiasis

Respiratory: Dyspnea, local alveolar osteitis (post oral surgery patients), pharyngitis, rhinitis, sinusitis, upper respiratory tract infection

Miscellaneous: Accidental injury

Rare but important or life-threatening: Acute renal failure, ageusia, agranulocytosis, albuminuria, alopecia, anaphylactoid reaction, anemia, angina pectoris, angioedema, anorexia, anosmia, anxiety, aplastic anemia, arthralgia, aseptic meningitis, ataxia, bronchitis, bronchospasm, bronchospasm (aggravated), cellulitis, cerebrovascular accident, chest pain, cholelithiasis, colitis (with bleeding), constipation, contact dermatitis, coronary artery disease, cough, cyst, cyst (NOS), cystitis, deafness, decreased hemoglobin, deep vein thrombosis, depression, dermatitis, diaphoresis, diverticulitis, drowsiness, dysphagia, dysuria, ecchymoses, edema, epistaxis, eructation, erythema multiforme, erythematous rash, esophageal perforation, esophagitis, exacerbation of hypertension, facial edema, fatigue, fever, flu-like symptoms, gangrene of skin or other tissue, gastritis, gastroenteritis, gastroesophageal reflux disease, gastrointestinal hemorrhage, hematuria, hemorrhoids, hepatic failure, hepatic necrosis, hepatitis, hiatal hernia, hot flash, hypercholesterolemia, hyperglycemia, hypersensitivity exacerbation, hypersensitivity reaction, hypertonia, hypoesthesia, hypoglycemia, hypokalemia, hyponatremia, increased appetite, increased blood urea nitrogen, increased creatine phosphokinase, increased nonprotein nitrogen, increased serum alkaline phosphatase, interstitial nephritis, intestinal obstruction, intracranial hemorrhage, jaundice, laryngitis, leg cramps, leukopenia, maculopapular rash, melena, migraine, myalgia, myocardial infarction, nervousness, osteoarthritis, pain, palpitations, pancreatitis, pancytopenia, paresthesia, peripheral pain, pneumonia, pruritus, pulmonary embolism, skin changes, skin photosensitivity, Stevens-Johnson syndrome, stomatitis, syncope, synovitis, tachycardia, tendonitis, tenesmus, thrombocythemia, thrombocytopenia, thrombophlebitis, tinnitus, toxic epidermal necrolysis, urinary frequency, urticaria, vasculitis, ventricular fibrillation, vertigo, weight gain, xeroderma, xerostomia