Fortum Vial (Fortaz Vial)1gm

Ceftazidime Information

Pronunciation

SEF tay zi deem

What is this drug used for?

• It is used to treat bacterial infections.

Frequently reported side effects of this drug

• Diarrhea

• Injection site irritation

Other side effects of this drug: Talk with your doctor right away if you have any of these signs of:

• Tremors

• Abnormal movements

• Confusion

• Extra muscle movement

• Dark urine

• Yellow skin or eyes

• Change in amount of urine passed

• Not able to pass urine

• Chills

• Sore throat

• Bruising

• Bleeding

• Severe loss of strength and energy

• Seizures

• Clostridioides (formerly Clostridium) difficile–associated diarrhea like abdominal pain or cramps, severe diarrhea or watery stools, or bloody stools.

• Signs of a significant reaction like wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.

Medication Safety Issues

Storage and Stability

Vials: Store intact vials at 20°C to 25°C (68°F to 77°F). Protect from light. Refer to manufacturer’s labeling for specific storage instructions for reconstituted solution and solution further diluted for IV infusion (varies by diluent).

Duplex container: Store unactivated containers at 20°C to 25°C (68°F to 77°F); excursions permitted to 15°C to 30°C (59°F to 86°F). Protect from light. Do not freeze. Unactivated duplex containers with foil strip removed from the drug chamber must be protected from light and used within 7 days at room temperature. Once activated, must be used within 12 hours if stored at room temperature or within 3 days if stored under refrigeration.

Premixed frozen solution: Store at -20°C (-4°F). Thawed solution is stable for 8 hours at room temperature or for 3 days under refrigeration; do not refreeze.

Adverse Reactions

Central nervous system: Seizure

Dermatologic: Pruritus, skin rash

Endocrine & metabolic: Increased gamma-glutamyl transferase, increased lactate dehydrogenase

Gastrointestinal: Diarrhea

Hematologic & oncologic: Agranulocytosis, eosinophilia, leukopenia, lymphocytosis, neutropenia, positive direct Coombs test (without hemolysis), thrombocythemia, thrombocytopenia

Hepatic: Increased serum alkaline phosphatase, increased serum ALT, increased serum AST

Hypersensitivity: Hypersensitivity reactions

Local: Inflammation at injection site, injection site phlebitis

Renal: Increased blood urea nitrogen, increased serum creatinine

Miscellaneous: Fever