What is this drug used for?
β’ It is used for many health problems like allergy signs, asthma, adrenal gland problems, blood problems, skin rashes, or swelling problems. This is not a list of all health problems that this drug may be used for. Talk with the doctor.
Frequently reported side effects of this drug
β’ Nausea
β’ Vomiting
β’ Trouble sleeping
β’ Restlessness
Other side effects of this drug: Talk with your doctor right away if you have any of these signs of:
β’ Infection
β’ High blood sugar like confusion, fatigue, increased thirst, increased hunger, passing a lot of urine, flushing, fast breathing, or breath that smells like fruit
β’ Adrenal gland problems like severe nausea, vomiting, severe dizziness, passing out, muscle weakness, severe fatigue, mood changes, lack of appetite, or weight loss
β’ Low potassium like muscle pain or weakness, muscle cramps, or an abnormal heartbeat
β’ Pancreatitis like severe abdominal pain, severe back pain, severe nausea, or vomiting
β’ Cushing syndrome like weight gain in upper back or abdomen; moon face; severe headache; or slow healing
β’ Skin changes like acne, stretch marks, slow healing, or hair growth
β’ DVT like swelling, warmth, numbness, change in color, or pain in the extremities
β’ Severe loss of strength and energy
β’ Fast heartbeat
β’ Confusion
β’ Sweating a lot
β’ Dizziness
β’ Passing out
β’ Shortness of breath
β’ Excessive weight gain
β’ Swelling of arms or legs
β’ Severe headache
β’ Fast heartbeat
β’ Slow heartbeat
β’ Abnormal heartbeat
β’ Chest pain
β’ Menstrual changes
β’ Joint pain
β’ Bone pain
β’ Vision changes
β’ Mood changes
β’ Behavioral changes
β’ Trouble with memory
β’ Trouble focusing
β’ Sensing things that seem real but are not
β’ Seizures
β’ Burning or numbness feeling
β’ Bruising
β’ Bleeding
β’ Severe abdominal pain
β’ Black, tarry, or bloody stools
β’ Vomiting blood
β’ Signs of a significant reaction like wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.
Note:Β This is not a comprehensive list of all side effects. Talk to your doctor if you have questions.
Pronunciation
(PRED ni sone)
Medication Safety Issues
Sound-alike/look-alike issues:
PredniSONE may be confused with methylPREDNISolone, Pramosone, prazosin, prednisoLONE, PriLOSEC, primidone, promethazine
Generic Availability: US
May be product dependent
Storage and Stability
Store at 25Β°C (77Β°F); excursions permitted to 15Β°C to 30Β°C (59Β°F to 86Β°F). Protect from light and moisture.
Oral solution, concentrate: Discard opened bottle after 90 days.
Adverse Reactions
Cardiovascular: Cardiac failure (in susceptible patients), hypertension
Central nervous system: Emotional lability, headache, increased intracranial pressure (with papilledema), myasthenia, psychiatric disturbance (including euphoria, insomnia, mood swings, personality changes, severe depression), seizure, vertigo
Dermatologic: Diaphoresis, facial erythema, skin atrophy, urticaria
Endocrine & metabolic: Cushingβs syndrome, decreased serum potassium, diabetes mellitus, fluid retention, growth suppression (children), hypokalemic alkalosis, hypothyroidism (enhanced), menstrual disease, negative nitrogen balance (due to protein catabolism), sodium retention
Gastrointestinal: Abdominal distention, carbohydrate intolerance, pancreatitis, peptic ulcer (with possible perforation and hemorrhage), ulcerative esophagitis
Hematologic & oncologic: Bruise, Kaposiβs sarcoma, petechia
Hepatic: Increased serum alkaline phosphatase, increased serum ALT, increased serum AST
Hypersensitivity: Anaphylaxis, hypersensitivity reaction
Infection: Infection
Neuromuscular & skeletal: Amyotrophy, aseptic necrosis of bones (femoral and humeral heads), osteoporosis, pathological fracture (long bones), rupture of tendon (particularly Achilles tendon), steroid myopathy, vertebral compression fracture
Ophthalmic: Exophthalmos, glaucoma, increased intraocular pressure, subcapsular posterior cataract
Miscellaneous: Wound healing impairment
Rare but important or life-threatening: Venous thrombosis (Johannesdottir 2013)
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