PARIT (Aciphex)20 mg – 30 tablet

Rabeprazole Sodium Information

Pronunciation

ra BEP ra zole

What is this drug used for?

• It is used to treat gastroesophageal reflux disease (GERD; acid reflux).

• It is used to treat heartburn.

• It is used to treat or prevent GI (gastrointestinal) ulcers caused by infection.

• It is used to treat or prevent ulcers of the swallowing tube (esophagus).

• It is used to treat syndromes caused by lots of stomach acid.

• It may be given to you for other reasons. Talk with the doctor.

Frequently reported side effects of this drug

• Headache

• Abdominal pain

• Nausea

• Vomiting

• Diarrhea

• Constipation

• Passing gas

• Sore throat

Other side effects of this drug: Talk with your doctor right away if you have any of these signs of:

• Low magnesium like mood changes; muscle pain or weakness; muscle cramps or spasms; seizures; tremors; lack of appetite; severe nausea or vomiting; or an abnormal heartbeat

• Kidney problems like not able to pass urine, blood in the urine, change in amount of urine passed, or weight gain

• Lupus like rash on the cheeks or other body parts, sunburn easy, muscle or joint pain, chest pain or shortness of breath, or swelling in the arms or legs

• Severe dizziness

• Passing out

• Bone pain

• Chills

• Excessive weight loss

• Severe loss of strength and energy

• Clostridioides (formerly Clostridium) difficile (C. diff)-associated diarrhea like abdominal pain or cramps, severe diarrhea or watery stools, or bloody stools

• Stevens-Johnson syndrome/toxic epidermal necrolysis like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in mouth, throat, nose, or eyes

• Signs of a significant reaction like wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.

Medication Safety Issues

Storage and Stability

Adverse Reactions

Cardiovascular: Peripheral edema (adults)

Central nervous system: Dizziness (adults), headache (more common in children and adolescents), pain (adults)

Gastrointestinal: Abdominal pain (more common in children), constipation (adults), diarrhea (more common in children and adolescents), flatulence (adults), nausea (children and adolescents), vomiting (more common in children), xerostomia

Hepatic: Hepatic encephalopathy (adults), hepatitis (adults), increased liver enzymes (adults)

Infection: Infection (adults)

Neuromuscular & skeletal: Arthralgia (adults), myalgia (adults)

Respiratory: Pharyngitis (adults)

Rare but important or life-threatening: Agranulocytosis, anaphylaxis, angioedema, blurred vision, bone fracture, bullous rash, Clostridium difficile associated diarrhea, coma, cutaneous lupus erythematous, delirium, disorientation, erythema multiforme, hemolytic anemia, hepatotoxicity (idiosyncratic) (Chalasani 2014), hyperammonemia, hypomagnesemia, increased thyroid stimulating hormone level, interstitial nephritis, jaundice, leukopenia, pancytopenia, pneumonia (interstitial), polyp (fundic gland), renal disease (chronic; Lazarus 2016), rhabdomyolysis, severe dermatological reaction, Stevens-Johnson syndrome, systemic lupus erythematosus, thrombocytopenia, toxic epidermal necrolysis, vertigo