Tenvir EM Tablet (Tenofovir 300mg Emtricitabine 200mg)
Composition
- • Each Film Coated tablet contains
- • Tenofovir Disoproxil Fumarate IP…..300mg
- • Emtricitabine IP……………………………200mg
Indication
Tenvir-EM is indicated in combination with other antiretroviral agents (such as non-nucleoside reverse transcriptase inhibitors or protease inhibitors) for the treatment of Human Immuno Deficiency virus (HIV-1) infection in adults, children, and infants aged above 4 months. It may also be used in very limited cases of long-term infections of liver caused by hepatitis B virus.
How it Works?
Tenofovir is an antiviral drug belonging to class nucleoside reverse transcriptase inhibitors (NRTIs). Its structure closely resembles the natural structure of viral DNA, that helps it to incorporateitself into the viral DNA. By doing so, it blocks the activity of an important viral enzyme reverse transcriptase which is involved in the replication of viral DNA, a process essential for survival of the virus.
Emtricitabine belongs to class of medication called antiretroviral medicines. It works by inhibiting the enzyme needed for DNA synthesis (nucleoside reverse transcriptase) thereby lowering the growth and decrease the amount of HIV in body.
Contraindications
Tenvir-EM is contraindicated in patients with previously demonstrated hypersensitivity to any of the components of the product.
Common side effects
Hyperglycemia, Abnormal dreams, Nausea, Increased liver enzyme, Swelling of eyes and lips., Abdominal pain, Dyspepsia, Vomiting, Insomnia, Very common: headache, Itching and rash, Hypertriglyceridemia, Diarrhea, Increased creatine kinase.common: neutropenia, Allergic reaction, Dizziness, Weakness and pain.uncommon: anemia
Myopathy ; kidney problems., Low potassium levels, Lactic acidosis ; liver problems, Increased liver enzymes, Pancreatitis ; muscle weakness; increased creatinine levels, Urge to vomit, Angioedema ; bone pain and fractures, Low blood phosphate level, Dizziness; loose motions, Vomiting; skin rashes, Weakness
EXPERT ADVICE
- • Do not take emtricitabine capsule/oral solution, if you are allergic to emtricitabine or any other ingredient of capsule/oral solution.
- • Stop taking emtricitabine, if you suffer from deep or rapid breathing, drowsiness, nausea (urge to vomit), vomiting and stomach pain.
- • Do not take emtricitabine, if you have kidney or liver problems; if you are overweight or have diabetes, high cholesterol.
FREQUENTLY ASKED QUESTIONS
Emtricitabine
Q. What class is emtricitabine? What is emtricitabine and tenofovir?
Emtricitabine and tenofovir belongs to class of antiretroviral medicines used for treatment of HIV infection
Q. What is emtricitabine used for?
Emtricitabine is used in combination with other medicines to treat human immunodeficiency virus (HIV) infection.
Q. How does emtricitabine work?
Emtricitabine works by inhibiting the enzyme for DNA synthesis (nucleoside reverse transcriptase) thereby lowering the growth and decrease the amount of human immunodeficiency virus (HIV) in body.
Q. Why emtricitabine is called FTC?
FTC is the short form assigned to emtricitabine for common referral term.
Q. Is tenofovir/emtricitabine teratogenic?
There are no evidence of tenofovir/emtricitabine causing harm during pregnancy. Do consult your doctor before use.
Tenofovir
Q. Is tenofovir safe during pregnancy/ Is tenofovir teratogenic?
Studies of tenofovir in animals do not indicate risk to fetus or any signs of teratogenicity. There are no adequate studies on tenofovir use in pregnant women. Tenofovir should be used during pregnancy only if clearly needed as advised by your doctor. Please consult your doctor before taking tenofovir if you are pregnant or planning to become pregnant.
Q. Is tenofovir a NRTI?
Yes. Tenofovir is an antiviral drug belonging to class nucleoside reverse transcriptase inhibitors (NRTIs).
Q. What is tenofovir/tenofovir disoproxil fumarate used for/ What does tenofovir treat?
Tenofovir is an antiviral drug used in combination with other drugs in the treatment of human immunodeficiency virus (HIV) infections. It may also be used in very limited cases of long-term infections of liver caused by hepatitis B virus.
Q. Is Viraday safe/ effective?
Viraday is a trade name for fixed-dose combination of drugs efavirenz, emtricitabine, and tenofovir. It is safe and effective if used at prescribed doses for the prescribed duration as advised by your doctor.
Q. Is viraday the same as atripla?
Yes. Viraday and atripla are trade names for fixed-dose combination of drugs efavirenz, emtricitabine, and tenofovir. They are used in the treatment of HIV.
Q. How does tenofovir work?
Tenofovir is an antiviral drug belonging to class nucleoside reverse transcriptase inhibitors (NRTIs). By the virtue of its structure that closely resembles the natural structure of viral DNA, tenofovir incorporates itself into the viral DNA. By doing so, it blocks the activity of an important viral enzyme reverse transcriptase which is involved in the replication of viral DNA, a process essential for survival of the virus.
Q. Does tenofovir cause hair loss?
Hair loss is not a known side effect of tenofovir.
Q. Does tenofovir cause lipodystrophy?
Tenofovir may cause lipodystrophy (build up or loss of body fat) especially in elderly patients with HIV. Physical examination of fat redistribution and monitoring of blood levels of lipids and sugar may be advised in elderly.
Q. How does tenofovir cause renal toxicity/renal failure?
Tenofovir is predominantly excreted by the kidneys. The part of kidneys involved in its excretion is called the proximal tubule. Studies indicate that tenofovir accumulation in the proximal tubule due to interaction with other drugs (eg. ritonavir) or prolonged use is responsible for kidney damage (renal toxicity). The kidney damage may then progress to kidney failure.
Q. Does tenofovir cure hepatitis B/ Is viraday effective/does viraday work?
Yes. Viraday is effective against human immunodeficiency virus (HIV) and some cases of hepatitis B. It is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
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