VENLOR XR (Effexor XR)37.5 mg – 100 tablet

Venlafaxine Information

Pronunciation

ven la FAX een

What is this drug used for?

• It is used to treat low mood (depression).

• It is used to treat anxiety.

• It is used to treat panic attacks.

• It may be given to you for other reasons. Talk with the doctor.

Frequently reported side effects of this drug

• Trouble sleeping

• Weight loss

• Anxiety

• Lack of appetite

• Loss of strength and energy

• Fatigue

• Tremors

• Constipation

• Sweating a lot

• Nausea

• Passing gas

• Dry mouth

• Nightmares

• Yawning

Other side effects of this drug: Talk with your doctor right away if you have any of these signs of:

• Depression like thoughts of suicide, anxiety, emotional instability, or confusion.

• Low sodium like headache, difficulty focusing, trouble with memory, confusion, weakness, seizures, or change in balance.

• Bleeding like vomiting blood or vomit that looks like coffee grounds; coughing up blood; blood in the urine; black, red, or tarry stools; bleeding from the gums; abnormal vaginal bleeding; bruises without a reason or that get bigger; or any severe or persistent bleeding.

• Passing out

• Vision changes

• Eye pain

• Eye irritation

• Eye edema

• Agitation

• Irritability

• Panic attacks

• Mood changes

• Behavioral changes

• Severe headaches

• Severe dizziness

• Seizures

• Chest pain

• Shortness of breath

• Decreased sex drive

• Sexual dysfunction

• Cough

• Bone pain

• Serotonin syndrome like dizziness, severe headache, agitation, sensing things that seem real but are not, fast heartbeat, abnormal heartbeat, flushing, tremors, sweating a lot, change in balance, severe nausea, or severe diarrhea.

• Signs of a significant reaction like wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.

Medication Safety Issues

Storage and Stability

Immediate-release tablets and extended-release capsules: Store at 20°C to 25°C (68°F to 77°F).

Extended-release tablets: Store at 25°C (77°F); excursions permitted between 15°C and 30°C (59°F and 86°F). Protect from moisture and humidity.

Adverse Reactions

Cardiovascular: Hypertension, hypotension, increased blood pressure, increased pulse, orthostatic hypotension, syncope, tachycardia, vasodilation

Central nervous system: Abnormal dreams, agitation, akathisia, anorgasmia, apathy, chills, confusion, depersonalization, dizziness, drowsiness, hallucination, hypertonia, insomnia, manic reaction, myoclonus, nervousness, paresthesia, seizure, suicidal ideation, yawning

Dermatologic: Alopecia, diaphoresis, ecchymoses, pruritus, skin photosensitivity, skin rash, urticaria

Endocrine & metabolic: Decreased libido, hypercholesterolemia, hypermenorrhea, increased serum triglycerides, orgasm abnormal (men), weight gain, weight loss

Gastrointestinal: Anorexia, bruxism, constipation, diarrhea, dysgeusia, gastrointestinal hemorrhage, nausea, vomiting, xerostomia

Genitourinary: Abnormal uterine bleeding, ejaculatory disorder, impotence, urinary frequency, urinary incontinence, urinary retention, urination disorder

Hematologic & oncologic: Hematoma, petechia

Neuromuscular & skeletal: Tremor, weakness

Ophthalmic: Accommodation disturbance, mydriasis, visual disturbance

Otic: Tinnitus

Respiratory: Epistaxis