Zipsydon (Geodon) 80mg – 50 tablet

Ziprasidone Information

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Pronunciation

zi PRAS i done

 

What is this drug used for?

• It is used to treat schizophrenia.

• It is used to treat bipolar problems.

• It may be given to you for other reasons. Talk with the doctor.

Frequently reported side effects of this drug

• Fatigue

• Restlessness

• Loss of strength and energy

• Nausea

• Vomiting

• Anxiety

• Constipation

• Diarrhea

• Dry mouth

• Headache

• Cough

• Weight gain

• Runny nose

• Injection site irritation

Other side effects of this drug: Talk with your doctor right away if you have any of these signs of:

• Infection

• High blood sugar like confusion, feeling sleepy, more thirst, hunger, passing urine more often, flushing, fast breathing, or breath that smells like fruit.

• Thoughts of suicide

• Severe dizziness

• Passing out

• Fast heartbeat

• Slow heartbeat

• Behavioral changes

• Mood changes

• Change in balance

• Abnormal movements

• Twitching

• Trouble swallowing

• Trouble speaking

• Abnormal heartbeat

• Seizures

• Vision changes

• Enlarged breasts

• Sexual dysfunction

• Nipple discharge

• No menstrual periods

• Erection that lasts more than 4 hours

• Neuroleptic malignant syndrome like fever, muscle cramps or stiffness, dizziness, very bad headache, confusion, change in thinking, fast heartbeat, abnormal heartbeat, or sweating a lot

• Tardive dyskinesia like unable to control body movements; tongue, face, mouth, or jaw sticking out; mouth puckering; and puffing cheeks

• Stevens-Johnson syndrome/toxic epidermal necrolysis like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in mouth, throat, nose, or eyes

• Signs of a significant reaction like wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.

 

Medication Safety Issues

 

Storage and Stability

Capsule: Store at 25°C (77°F); excursion permitted to 15°C to 30°C (59°F to 86°F).

Vials for injection: Store at 25°C (77°F); excursion permitted to 15°C to 30°C (59°F to 86°F). Protect from light. Following reconstitution, injection may be stored at room temperature up to 24 hours or under refrigeration for up to 7 days. Protect from light.

 

Adverse Reactions

Note: Although minor QTc prolongation (mean: 10 msec at 160 mg/day) may occur more frequently, clinically relevant prolongation (>500 msec) was rare and less than placebo.

Cardiovascular: Angina pectoris, bradycardia, chest pain, facial edema, hypertension, orthostatic hypotension (may be dose-related), peripheral edema, tachycardia

Central nervous system: Agitation, akathisia, amnesia, anorgasmia, anxiety (may be dose-related), ataxia, atrial fibrillation, chills, confusion, delirium, dizziness (includes lightheadedness; may be dose-related), drowsiness (may be dose-related), dystonia (may be dose-related), extrapyramidal reaction, falling, flank pain, headache, hostility, hypoesthesia, hypothermia, insomnia, male sexual disorder, paralysis, personality disorder, speech disturbance, vertigo, withdrawal syndrome

Dermatologic: Alopecia, contact dermatitis, diaphoresis, ecchymoses, eczema, exfoliative dermatitis, fungal dermatitis, furunculosis, maculopapular rash, skin photosensitivity, skin rash (may be dose-related), urticaria, vesiculobullous dermatitis

Endocrine & metabolic: Albuminuria, amenorrhea, dehydration, glycosuria, hypercholesterolemia, hyperglycemia, hypermenorrhea, hypokalemia, increased lactate dehydrogenase, increased thirst, weight gain

Gastrointestinal: Abdominal pain, anorexia (may be dose-related), buccoglossal syndrome, constipation, diarrhea, dysmenorrhea, dyspepsia, dysphagia, nausea, sialorrhea (may be dose-related), vomiting, xerostomia (may be dose-related)

Genitourinary: Hematuria, impotence, lactation, priapism, urinary retention

Hematologic & oncologic: Anemia, eosinophilia, leukocytosis, leukopenia, lymphadenopathy, rectal hemorrhage

Hepatic: Increased serum alkaline phosphatase, increased serum transaminases

Hypersensitivity: Tongue edema

Local: Pain at injection site

Neuromuscular & skeletal: Abnormal gait, akinesia, choreoathetosis, cogwheel rigidity, dysarthria, dyskinesia, hyperkinesia, hypertonia, hypokinesia, hypotonia, increased creatine phosphokinase, myalgia, neuropathy, paresthesia, tenosynovitis, tremor (may be dose-related), twitching, weakness (may be dose-related)

Ophthalmic: Blepharitis, cataract, conjunctivitis, diplopia, oculogyric crisis, photophobia, visual disturbance (may be dose-related), xerophthalmia

Otic: Tinnitus

Renal: Polyuria

Respiratory: Cough, dyspnea, epistaxis, flu-like symptoms, pharyngitis, pneumonia, respiratory tract infection, rhinitis

Miscellaneous: Accidental injury, fever, motor vehicle accident